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Answer:

D. High levels of DNA repair mechanisms

Explanation:

Cancer cells are characterized by their ability to sustain chronic proliferation, evade growth suppressors, resist cell death, enable replicative immortality, induce angiogenesis, and activate invasion and metastasis. However, they typically have defective DNA repair mechanisms, which contribute to genetic instability and mutation accumulation, not high levels of DNA repair.

Explanation:

Cannulation of the ampulla of Vater (papilla) allows access to the biliary and pancreatic ducts during ERCP.

Osteosarcoma

Explanation:

The described radiographic features, including mixed lucent and sclerotic lesion, cortical breach, and soft-tissue extension, are consistent with osteosarcoma.

Answer:

C. Shortened externally rotated leg

Explanation:

A shortened externally rotated leg in an older patient suggests a fracture of the proximal femur.

Explanation:

Ultrasound is the first-line investigation for suspected acute cholecystitis due to its high sensitivity and specificity for detecting gallstones and assessing gallbladder wall thickening and distension. It is a non-invasive, readily available, and cost-effective diagnostic tool.